Association between polymorphisms in the progesterone receptor gene and endometriosis

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Association between polymorphisms in the progesterone receptor gene and endometriosis.

The progesterone receptor (PR) is a candidate gene for the development of endometriosis, a complex disease with strong hormonal features, common in women of reproductive age. We typed the 306 base pair Alu insertion (AluIns) polymorphism in intron G of PR in 101 individuals, estimated linkage disequilibrium (LD) between five single-nucleotide polymorphisms (SNPs) across the PR locus in 980 Aust...

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The Association between TNF-alpha Gene Polymorphisms and Endometriosis in An Iranian Population

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Association between the Melanocortin-4 Receptor (MC4R) Gene Polymorphisms and Growth Trait in Sumba Ongole Cattle

Melanocortin-4 receptor (MC4R) gene has been known as a candidate gene for growth traits in livestock. This research was aimed to identify the polymorphism of MC4R gene and its association with growth traits in Sumba Ongole (SO) cattle. The growth traits data consist of body weight and body size. Eighty four blood samples were collected and used for DNA isolation. The...

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Frequency of Polymorphism Alu Insertion in Progesterone Receptor Gene in Endometriosis

Background and Aims: This research aimed to study a possible link between endometriosis and polymorphism of the progesterone receptor gene. Materials and Methods: The control group consisted of 86 women without endometriosis and the case group comprised 86 patients with a diagnosis of endometriosis by laparoscopy. Genotypes for Alu insertion polymorphisms (A1/A1, A1/A2 and A2/A2) were descri...

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Progesterone receptor gene polymorphisms and risk of endometriosis: results from an international collaborative effort.

OBJECTIVE To investigate the association between self-reported endometriosis and the putative functional promoter +331C/T single nucleotide polymorphism and the PROGINS allele. DESIGN Control subjects from ovarian cancer case-control studies participating in the international Ovarian Cancer Association Consortium. The majority of controls are drawn from population-based studies. SETTING An ...

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ژورنال

عنوان ژورنال: MHR: Basic science of reproductive medicine

سال: 2005

ISSN: 1460-2407,1360-9947

DOI: 10.1093/molehr/gah221